1. What does this protein make up or do? thyroid dyshormonogenesis
Chapter 8: Chromosome 8
DNA Sequence
Chromosome
267,987 bp
Name of Protein 8
Name of Gene
thyroglobulin TG
transcription .
Amino acid sequence
mRNA
2768 aa
translation
Cytoplasm
What does this protein make up or do?
Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine
A Cell
Nucleus
Condition/Disease
thyroid dyshormonogenesis

2. Description of Thyroid Dyshormonogenesis
Symptoms and characteristics
Genetic Defect that causes Thyroid swelling
This is due to the Thyroid gland not producing enough of important hormones
Thyroid Dyshormonogenesis is cured by taking a pill from your doctor to cut down the swelling.
Swollen Thyroid

3. Thyroid Dyshormonogenisis
Dyshormonogenesis is caused by hereditary defects in the steps of thyroid hormone synthesis and secretion. It is transmitted in a recessive manner but at least one condition has autosomal dominant inheritance.
Iodine is added to all drinking water, it is a hormone that reduces the chance of thyroid dyshormonogenisis.
infants start on treatment early when detected at birth
Thyroid Dyshormnogenisis affects IQ and the person’s ability to learn, however the sooner treated the better.

4. References
Oprahnet. Dr Stephen LAFRANCHI [cited 2015 March 2]. Available at URL:
Genetics Home Reference [cited 2015 March 2]. Available at URL: