1. Nat. Rev. Endocrinol. doi:10.1038/nrendo.2017.97
Figure 4 Gene expression profiling of acute and chronic stress compared with cortisol injections
Figure 4 | Gene expression profiling of acute and chronic stress compared with cortisol injections. The Venn diagram shows minimal overlap between corticosterone-injected animals and acute forced swim or chronic restraint stressors, demonstrating the substantial effects of stress mediators other than glucocorticoids on gene expression in the hippocampus. Up and down arrows indicate numbers of genes with increased or decreased expression, respectively. Each circle represents a comparison between stress or corticosterone injection and control animals. Corticosterone circle is compared to vehicle-injected control; stress circles are compared to naive unstressed animals. Image adapted with permission from Ref. 77, Macmillan Publishers Limited.
Gray, J. D. et al. (2017) Genomic and epigenomic mechanisms of glucocorticoids in the brain
Nat. Rev. Endocrinol. doi: /nrendo