1. Determination of serum propofol concentrations by breath analysis using ion mobility spectrometry 
T. Perl, E. Carstens, A. Hirn, M. Quintel, W. Vautz, J. Nolte, M. Jünger 
British Journal of Anaesthesia 
Volume 103, Issue 6, Pages (December 2009)
DOI: /bja/aep312
Copyright © 2009 British Journal of Anaesthesia Terms and Conditions

2. Fig 1 Schematic diagram of an MCC–IMS.
British Journal of Anaesthesia  , DOI: ( /bja/aep312)
Copyright © 2009 British Journal of Anaesthesia Terms and Conditions

3. Fig 2
Schematic diagram of the sample acquisition device mounted on the respirator circuit. The valve control toggles the two-way valve to the sample loop if carbon dioxide exceeds a level of 3.33 kPa. A/D, analogue to digital.
British Journal of Anaesthesia  , DOI: ( /bja/aep312)
Copyright © 2009 British Journal of Anaesthesia Terms and Conditions

4. Fig 3
Linear regression analysis of propofol in exhaled air (cAP) (ppb) as determined by MCC–IMS vs propofol serum concentrations (cPP) determined by GC–MS. The solid line indicates the regression line, and the dotted line indicates the 95% confidence interval. The correlation coefficient (r2) was 0.73.
British Journal of Anaesthesia  , DOI: ( /bja/aep312)
Copyright © 2009 British Journal of Anaesthesia Terms and Conditions

5. Fig 4
Comparison of exhaled propofol concentrations (cAP) and serum propofol concentrations (cPP). Mean [(cPPnorm+cAPnorm)/2]=average value of normalized serum (cPP)+alveolar (cAP) concentrations. Delta=difference between normalized propofol concentration in serum and breath (cPPnorm and cAPnorm). Plot according to Bland and Altman, modified as described by Mayevsky and colleagues.17 Bias (precision) was −10.5% (12.3%) (solid line) with 95% limits of agreement of –35.1% and 14.1% (dotted lines).
British Journal of Anaesthesia  , DOI: ( /bja/aep312)
Copyright © 2009 British Journal of Anaesthesia Terms and Conditions