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Withdrawal of GnRH agonist decreases oestradiol and VEGF concentrations in high responders  Li-Jun Ding, Bin Wang, Xiao-Yue Shen, Gui-Jun Yan, Ning-Yuan.

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Presentation on theme: "Withdrawal of GnRH agonist decreases oestradiol and VEGF concentrations in high responders  Li-Jun Ding, Bin Wang, Xiao-Yue Shen, Gui-Jun Yan, Ning-Yuan."— Presentation transcript:

1 Withdrawal of GnRH agonist decreases oestradiol and VEGF concentrations in high responders 
Li-Jun Ding, Bin Wang, Xiao-Yue Shen, Gui-Jun Yan, Ning-Yuan Zhang, Ya-Li Hu, Hai-Xiang Sun  Reproductive BioMedicine Online  Volume 27, Issue 2, Pages (August 2013) DOI: /j.rbmo Copyright © 2013 Reproductive Healthcare Ltd. Terms and Conditions

2 Figure 1 Changes in CYP19A1 and vascular endothelial growth factor (VEGF) expression in women undergoing the ovarian stimulation cycles, as observed in the GnRH agonist withdrawal treatment group and the GnRH agonist continuation treatment group. (a and b) The expression of CYP19A1 (a) and VEGF (b) in the luteinized granulosa cells from the retrieved COC were detected by quantitative real-time PCR and normalized to the expression of ribosomal protein 18S. (c and d) VEGF concentrations in plasma on the day of HCG administration (c) and in follicular fluids from the dominant retrieved COC (d) were analysed by enzyme-linked immunosorbent assay. The data are representative of four independently performed experiments. ∗P<0.05 versus control. Reproductive BioMedicine Online  , DOI: ( /j.rbmo ) Copyright © 2013 Reproductive Healthcare Ltd. Terms and Conditions


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