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Diagnostic Performance of Integrated Positron Emission Tomography/Computed Tomography for Mediastinal Lymph Node Staging in Non-small Cell Lung Cancer:

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Presentation on theme: "Diagnostic Performance of Integrated Positron Emission Tomography/Computed Tomography for Mediastinal Lymph Node Staging in Non-small Cell Lung Cancer:"— Presentation transcript:

1 Diagnostic Performance of Integrated Positron Emission Tomography/Computed Tomography for Mediastinal Lymph Node Staging in Non-small Cell Lung Cancer: A Bivariate Systematic Review and Meta-Analysis  Yan-Ling Lv, Dong-Mei Yuan, Ke Wang, Xiao-Hui Miao, Qian Qian, Shu-Zhen Wei, Xi-Xu Zhu, Yong Song, PhD, MD  Journal of Thoracic Oncology  Volume 6, Issue 8, Pages (August 2011) DOI: /JTO.0b013e31821d4384 Copyright © 2011 International Association for the Study of Lung Cancer Terms and Conditions

2 FIGURE 1 Quality assessment of 20 included studies.
Journal of Thoracic Oncology 2011 6, DOI: ( /JTO.0b013e31821d4384) Copyright © 2011 International Association for the Study of Lung Cancer Terms and Conditions

3 FIGURE 2 Meta-analysis of sensitivity (SEN) and specificity (SPE) of integrated positron emission tomography/computed tomography (PET/CT) for mediastinal lymph nodes (MLN) staging in non-small cell lung cancer (NSCLC). A, Based on a patient-based analysis. B, Based on an MLN-based analysis. Journal of Thoracic Oncology 2011 6, DOI: ( /JTO.0b013e31821d4384) Copyright © 2011 International Association for the Study of Lung Cancer Terms and Conditions

4 FIGURE 3 Summary receiver operating characteristic (SROC) curves from the bivariate model of integrated positron emission tomography/computed tomography (PET/CT) for mediastinal lymph nodes (MLN) staging in non-small cell lung cancer (NSCLC). A, Based on a patient-based analysis. B, Based on an MLN-based analysis. Journal of Thoracic Oncology 2011 6, DOI: ( /JTO.0b013e31821d4384) Copyright © 2011 International Association for the Study of Lung Cancer Terms and Conditions

5 FIGURE 4 Forest plot of subgroup analyses for sensitivity (SEN) and specificity (SPE). *p < 0.05; **p < 0.01; ***p < Journal of Thoracic Oncology 2011 6, DOI: ( /JTO.0b013e31821d4384) Copyright © 2011 International Association for the Study of Lung Cancer Terms and Conditions

6 FIGURE 5 The funnel plot of publication bias. A, Based on a patient-based analysis. B, Based on an mediastinal lymph nodes (MLN)-based analysis. Journal of Thoracic Oncology 2011 6, DOI: ( /JTO.0b013e31821d4384) Copyright © 2011 International Association for the Study of Lung Cancer Terms and Conditions

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