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Volume 87, Issue 2, Pages (July 2015)

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1 Volume 87, Issue 2, Pages 252-256 (July 2015)
BigNeuron: Large-Scale 3D Neuron Reconstruction from Optical Microscopy Images  Hanchuan Peng, Michael Hawrylycz, Jane Roskams, Sean Hill, Nelson Spruston, Erik Meijering, Giorgio A. Ascoli  Neuron  Volume 87, Issue 2, Pages (July 2015) DOI: /j.neuron Copyright © 2015 Elsevier Inc. Terms and Conditions

2 Figure 1 Bioimage Informatics Matchmaking
In neuroscience labs worldwide, neuronal morphology image stacks are acquired through multiple microscopy modalities from a diverse array of experimental preparations. At the same time, a broad range of reconstruction algorithms are continuously developed using various programming languages, computational platforms, and custom test beds. Harnessing powerful supercomputers and the open source community, BigNeuron brings together tens of thousands of state-of-the-art 3D neuronal images with all major classes of automated tracing systems to generate an unprecedented number of digital morphological reconstructions. Expert cross-analysis of the initial bench testing dataset against manually curated gold standards will generate a unique toolbox of morphometric measurements aimed to stimulate further development. Neuron  , DOI: ( /j.neuron ) Copyright © 2015 Elsevier Inc. Terms and Conditions

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