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Azathioprine-Induced Lymphoma Manifesting as Fulminant Hepatic Failure

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Presentation on theme: "Azathioprine-Induced Lymphoma Manifesting as Fulminant Hepatic Failure"— Presentation transcript:

1 Azathioprine-Induced Lymphoma Manifesting as Fulminant Hepatic Failure
Humberto I. Aguilar, MD, Lawrence J. Burgart, MD, Alex Geller, MD, Jorge Rakela, MD  Mayo Clinic Proceedings  Volume 72, Issue 7, Pages (July 1997) DOI: / Copyright © 1997 Mayo Foundation for Medical Education and Research Terms and Conditions

2 Fig. 1 Abdominal ultrasonogram, showing multiple hypoechoic masses (arrows) within liver. Mayo Clinic Proceedings  , DOI: ( / ) Copyright © 1997 Mayo Foundation for Medical Education and Research Terms and Conditions

3 Fig. 2 Fine-needle aspiration liver biopsy specimen, showing that anaplastic large cell lymphoma cells have effaced liver architecture and totally displaced hepatocytes. Note widespread pleomorphism of neoplastic cells including multinucleated cells. (Hematoxylin-eosin; original magnification, ×400.) Mayo Clinic Proceedings  , DOI: ( / ) Copyright © 1997 Mayo Foundation for Medical Education and Research Terms and Conditions

4 Fig. 3 Immunoperoxidase stain with use of antibody to CD30 (BerH2), showing uniform, strong membrane staining of lymphoma cells. (Original magnification, ×400.) Mayo Clinic Proceedings  , DOI: ( / ) Copyright © 1997 Mayo Foundation for Medical Education and Research Terms and Conditions


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