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The origin of cancer stem cells
Hien T. Dang, Anuradha Budhu, Xin W. Wang Journal of Hepatology Volume 60, Issue 6, Pages (June 2014) DOI: /j.jhep Copyright © Terms and Conditions
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Fig. 1 The impact of the liver milieu on preneoplastic lesions. Within the cirrhotic liver are foci of altered hepatocytes (FAH) that harbors multiple hepatic cell lineages including aggregates of hepatic cancer progenitor cells (HcPCs). The damaged liver provides a microenvironment that is conducive for tumor progression, which allows HcPCs to become cancer stem cells (CSCs). Journal of Hepatology , DOI: ( /j.jhep ) Copyright © Terms and Conditions
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