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Hormones that affect metabolism
Ms Manning SBI4U0
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Thyroid Gland Lies in the anterior neck just below the larynx.
Two lobes, located on either side of the trachea. Beginning course details and/or books/materials needed for a class/project.
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Thyroid Gland - Hormones
Thyroxine (T4) & Triiodothyronine (T3) Regulate body metabolism and the growth and differentiation of body tissues T4 stimulates the oxidation of glucose and other nutrients T4 = metabolism A schedule design for optional periods of time/objectives.
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T4 and T3 Trigger : Target: Effect:
low MR/cold release of TSH from ant. pit. ** structures require iodine! Target: Many tissues Effect: Increase metabolism Protein synthesis Increase production of ATP Objectives for instruction and expected results and/or skills developed from learning.
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Feedback Loop - Metabolism
Hypothalamus releases thyroid releasing hormone (TRH) Receptors in hypothalamus detect low MR Stimulus – Low Metabolic Rate Anterior pituitary releases thyroid stimulating hormone (TSH) Relative vocabulary list. Response – body cells increase oxidation of glucose MR Thyroxine released by thyroid
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Low Metabolic Rate Stimulus – Low Metabolic Rate/Cold Monitor – receptors in hypothalamus Co-ord #1 – hypothalamus releases thyroid releasing hormone (TRH) Co-ord #2 – pituitary gland releases thyroid stimulating hormone (TSH) Co-ord #3 – thyroid gland releases thyroxine Regulator – body cells oxidation of glucose Introductory notes.
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Metabolism Calcitonin Trigger increased blood calcium Target - bone
Effect - deposit calcium in bone A list of procedures and steps, or a lecture slide with media.
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Thyroid Disorders Hypothyroidism, or Myxedema Myxedema symptoms:
Facial bloating weakness cold intolerance lethargy altered mental status oily skin and hair Goiter (xs TSH)
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Goiter Low iodine = thyroxine production drops = more and more TSH produced = over stimulus of the thyroid = cells continue to develop = enlarged thyroid
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Hyperthyroidism Caused by an increase in T4/T3 production
Commonly called Graves’ disease Signs and symptoms: insomnia, fatigue tachycardia hypertension heat intolerance weight loss Long term hyperthyroidism causes Exopthalmos
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Parathyroid Glands small, pea-shaped glands, located in
the neck near the thyroid usually 4 - can vary regulate the level of calcium in the body Example graph/chart.
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Parathyroid Hormone (PTH)
parathormone Trigger: low level of calcium in blood Target : bone, kidney, intestine Effect : reabsorb calcium into blood Hypocalcemia can result if parathyroids are removed or destroyed. "tetany" Example graph/chart.
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Conclusion to course, lecture, et al.
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