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Pronounced facial flushing and persistent erythema of rosacea effectively treated by carvedilol, a nonselective β-adrenergic blocker  Chia-Chi Hsu, MD,

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Presentation on theme: "Pronounced facial flushing and persistent erythema of rosacea effectively treated by carvedilol, a nonselective β-adrenergic blocker  Chia-Chi Hsu, MD,"— Presentation transcript:

1 Pronounced facial flushing and persistent erythema of rosacea effectively treated by carvedilol, a nonselective β-adrenergic blocker  Chia-Chi Hsu, MD, Julia Yu-Yun Lee, MD  Journal of the American Academy of Dermatology  Volume 67, Issue 3, Pages (September 2012) DOI: /j.jaad Copyright © 2012 American Academy of Dermatology, Inc. Terms and Conditions

2 Fig 1 Patient 11. A, Before carvedilol treatment, facial flushing and persistent erythema were treated with doxycycline 100 mg once daily (qd) and dexamethasone 0.5 mg qd. B, After starting carvedilol mg 3 times a day (tid) for 2 weeks, then 6.25 mg tid for another 2 weeks, there was significant clinical improvement. C, Further improvement of facial erythema when carvedilol was increased to 25 mg/d. D, Changes of treatment regimen, visual analog scale (VAS) score, and cheek temperature over time. Note transient increase of VAS and cheek temperature when dexamethasone was tapered to 0.25 mg qd. But this flareup was reversed when dose of carvedilol was increased to 25 mg/d. This dose adjustment also allowed cessation of dexamethasone. Journal of the American Academy of Dermatology  , DOI: ( /j.jaad ) Copyright © 2012 American Academy of Dermatology, Inc. Terms and Conditions

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