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Published byΠαραμονος Κουρμούλης Modified over 6 years ago
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Learning “...relatively permanent changes in behavior produced by experience” Learning involves changes in the nervous system produced by experiences
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A variety of models to study changes that occur via learning
Using slices from a hippocampus and measuring LTP (long-term potentiation)
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hippocampus
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A variety of models to study changes that occur via learning
Using slices from a hippocampus Using a giant sea slug (Aplysia)
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How might it happen?
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More postsynaptic receptors
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Increases in axonal sprouting
Increased postsynaptic response
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is there evidence for this?
so – possible changes in neuronal response after repeated activity of circuits- is there evidence for this? YES!
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What has been shown? Consequences: Aplysia – giant sea slug
habituation – what causes it? less Ca+2 influx to presynaptic ending with repeated stimulation Consequences:
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many models to study neural changes during learning
Aplysia – giant sea slug see changes during sensitization more Ca+2 influx to presynaptic ending with repeated pairings Consequences:
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2nd model hippocampal slice model and LTP (long-term potentiation)
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LTP – long-term potentiation
increased sensitivity of circuit with repeated activity
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Copyright © Allyn & Bacon 2007
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Copyright © Allyn & Bacon 2007
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conclusions learning and memory require not only neural activity but some sort of change in the neural circuitry that persists beyond the event….
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