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Correction of Abdominal Distention by Biofeedback-Guided Control of Abdominothoracic Muscular Activity in a Randomized, Placebo-Controlled Trial Elizabeth Barba, Anna Accarino, Fernando Azpiroz Clinical Gastroenterology and Hepatology Volume 15, Issue 12, Pages (December 2017) DOI: /j.cgh Copyright © 2017 AGA Institute Terms and Conditions
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Figure 1 Flow chart. At study entry, 48 patients were randomized; 2 patients allocated to placebo withdrew and 2 patients in the biofeedback group were lost to follow-up (did not complete the questionnaires) and were not included in the primary outcome analysis. Patients who did not improve with placebo (n = 19) received biofeedback treatment afterward. All patients who received biofeedback (n = 41 valid for analysis) were followed up at 1, 3, and 6 months after treatment. Clinical Gastroenterology and Hepatology , DOI: ( /j.cgh ) Copyright © 2017 AGA Institute Terms and Conditions
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Figure 2 Effects during treatment on abdominothoracic muscle activity. Changes at the end of the third treatment session from pretreatment distention session. Biofeedback significantly modified the activity of abdominothoracic muscles (n = 24), whereas placebo (n = 22) had no effect. Several patients did not tolerate esophageal intubation in all sessions, hence diaphragmatic EMG recordings during both the pretreatment distention session and the third treatment session for paired analysis were only partly available (n = 11 in the biofeedback group; n = 11 in the placebo group). Clinical Gastroenterology and Hepatology , DOI: ( /j.cgh ) Copyright © 2017 AGA Institute Terms and Conditions
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Figure 3 Effects during treatment on abdominal distention (subjective sensation and girth). Changes at the end of the third treatment session from pretreatment distention session. Biofeedback (n = 24) reduced the sensation of abdominal distention and girth, whereas placebo (n = 22) had no effect. Clinical Gastroenterology and Hepatology , DOI: ( /j.cgh ) Copyright © 2017 AGA Institute Terms and Conditions
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Figure 4 Effects after treatment. Individual abdominal distention scores (averaged over 10 consecutive days) before and immediately after treatment, either biofeedback (FD; n = 22) or placebo (n = 22). Patients who did not improve with placebo (n = 19) received biofeedback treatment afterward. Clinical Gastroenterology and Hepatology , DOI: ( /j.cgh ) Copyright © 2017 AGA Institute Terms and Conditions
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