1. Mutant p53 in Cancer: New Functions and Therapeutic Opportunities
Patricia A.J. Muller, Karen H. Vousden 
Cancer Cell 
Volume 25, Issue 3, Pages (March 2014)
DOI: /j.ccr
Copyright © 2014 The Authors Terms and Conditions

2. Figure 1
Strategies that Are Currently Being Explored to Target Mutant p53
Depicted in red are schematics of the strategies that are currently being explored to target p53 mutant-expressing cancers. These strategies include promotion of mutant p53 degradation through the proteasome and autophagy pathways, restoration of wild-type p53 activity, interference with the interaction between mutant p53 and other proteins, and interference in signaling pathways downstream of mutant p53.
Cancer Cell  , DOI: ( /j.ccr )
Copyright © 2014 The Authors Terms and Conditions