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Long-term outcome after infliximab for refractory ulcerative colitis

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Presentation on theme: "Long-term outcome after infliximab for refractory ulcerative colitis"— Presentation transcript:

1 Long-term outcome after infliximab for refractory ulcerative colitis
Marc Ferrante, Séverine Vermeire, Herma Fidder, Fabian Schnitzler, Maja Noman, Gert Van Assche, Gert De Hertogh, Ilse Hoffman, Andre D'Hoore, Kristel Van Steen, Karel Geboes, Freddy Penninckx, Paul Rutgeerts  Journal of Crohn's and Colitis  Volume 2, Issue 3, Pages (September 2008) DOI: /j.crohns Copyright © Terms and Conditions

2 Figure 1 Sustained clinical response to IFX in 81 outpatients achieving clinical response in the overall cohort (A) and in 60 patients with refractory colitis achieving clinical response outside ACT1 (B). Journal of Crohn's and Colitis 2008 2, DOI: ( /j.crohns ) Copyright © Terms and Conditions

3 Figure 2 Colectomy-free survival after first IFX infusion in the whole cohort of 121 outpatients with refractory UC (A) and in the subgroup of 91 patients with who received IFX outside ACT1 (B). Journal of Crohn's and Colitis 2008 2, DOI: ( /j.crohns ) Copyright © Terms and Conditions

4 Figure 3 Colectomy-free survival after first IFX infusion stratified by short-term clinical response (A), short-term mucosal healing (B), baseline C-reactive protein level (C), short-term CRP drop (D), previous treatment with IV corticosteroids and/or cyclosporine (E), and MDR1 C3435T genotype (F). Journal of Crohn's and Colitis 2008 2, DOI: ( /j.crohns ) Copyright © Terms and Conditions


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