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Clinical trials in luminal Crohn's disease: A historical perspective

Published bySvend Aagaard Modified over 5 years ago

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1 Clinical trials in luminal Crohn's disease: A historical perspective
Pieter Hindryckx, Filip Baert, Ailsa Hart, Alessandro Armuzzi, Julian Panès, Laurent Peyrin-Biroulet  Journal of Crohn's and Colitis  Volume 8, Issue 11, Pages (November 2014) DOI: /j.crohns Copyright © 2014 European Crohn's and Colitis Organisation Terms and Conditions

2 Figure 1 Timeline with the milestones in clinical trial development in Crohn's disease before the advent on anti-TNF agents. (CT: clinical trial, RCT: randomized controlled trials, NCCDS: National cooperative Crohn's disease study, CDAI: Crohn's disease activity index, ECCDS: European cooperative Crohn's disease study, CDEIS: Crohn's disease endoscopic activity index of severity). Journal of Crohn's and Colitis 2014 8, DOI: ( /j.crohns ) Copyright © 2014 European Crohn's and Colitis Organisation Terms and Conditions

3 Figure 2 Overview of the evolution of primary endpoints of CTs in luminal CD. Journal of Crohn's and Colitis 2014 8, DOI: ( /j.crohns ) Copyright © 2014 European Crohn's and Colitis Organisation Terms and Conditions

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