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Clinical Practice Guidelines for Hemodialysis Adequacy, Update 2006

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Presentation on theme: "Clinical Practice Guidelines for Hemodialysis Adequacy, Update 2006"— Presentation transcript:

1 Clinical Practice Guidelines for Hemodialysis Adequacy, Update 2006
American Journal of Kidney Diseases  Volume 48, Pages S2-S90 (July 2006) DOI: /j.ajkd Copyright © 2006 National Kidney Foundation, Inc. Terms and Conditions

2 Fig 1 Impact of ultrafiltration on delivered dose of HD measured by using spKt/V and URR. The curves are derived from formal single-pool modeling of urea kinetics assuming a 3-hour dialysis, no RKF, and a volume of urea distribution that is 58% of BW. ΔWt refers to net ultrafiltration losses as a fraction of final BW. Reprinted with permission.67 American Journal of Kidney Diseases  , S2-S90DOI: ( /j.ajkd ) Copyright © 2006 National Kidney Foundation, Inc. Terms and Conditions

3 Fig 2 eKt/V as a function of dialysis treatment time. The rate equations for eKt/V (lower 3 lines) predict that dialysis efficiency decreases as time is shortened, creating a larger difference between eKt/V and spKt/V. (— spKt/V, – – Daugirdas, Tattersall et al,70 – - – Leypoldt et al71 ) American Journal of Kidney Diseases  , S2-S90DOI: ( /j.ajkd ) Copyright © 2006 National Kidney Foundation, Inc. Terms and Conditions

4 Fig 3 Components of postdialysis urea (BUN) rebound. See text for explanation. Reprinted with permission.82 American Journal of Kidney Diseases  , S2-S90DOI: ( /j.ajkd ) Copyright © 2006 National Kidney Foundation, Inc. Terms and Conditions

5 Fig 4 Stop-dialysate method for postdialysis blood sampling. Mean arterial and venous blood urea concentrations after stopping dialysate flow are expressed as a fraction of the blood urea concentration in the contralateral arm at time zero (n = 10). The data suggest that, for practical purposes, 3 minutes after stopping dialysate flow, equilibration has occurred between inlet and outlet blood. Reprinted with permission.96 American Journal of Kidney Diseases  , S2-S90DOI: ( /j.ajkd ) Copyright © 2006 National Kidney Foundation, Inc. Terms and Conditions

6 Fig 5 Illustration of the “lag phenomenon.” The secondary decrease in blood pressure seen at 5 months unassociated with a change in ECV was observed in all 8 patients studied. Reprinted with permission.125 American Journal of Kidney Diseases  , S2-S90DOI: ( /j.ajkd ) Copyright © 2006 National Kidney Foundation, Inc. Terms and Conditions

7 Fig 6 Effect of residual native kidney clearance (Kr). The increase in BUN levels from the post-BUN level to the next pre-BUN level is modulated by Kr, as shown in the lower curve. The result is a pre-BUN level that is lower when compared to the pre-BUN level in the absence of Kr (upper line). American Journal of Kidney Diseases  , S2-S90DOI: ( /j.ajkd ) Copyright © 2006 National Kidney Foundation, Inc. Terms and Conditions

8 American Journal of Kidney Diseases 2006 48, S2-S90DOI: (10. 1053/j
American Journal of Kidney Diseases  , S2-S90DOI: ( /j.ajkd ) Copyright © 2006 National Kidney Foundation, Inc. Terms and Conditions

9 American Journal of Kidney Diseases 2006 48, S2-S90DOI: (10. 1053/j
American Journal of Kidney Diseases  , S2-S90DOI: ( /j.ajkd ) Copyright © 2006 National Kidney Foundation, Inc. Terms and Conditions

10 American Journal of Kidney Diseases 2006 48, S2-S90DOI: (10. 1053/j
American Journal of Kidney Diseases  , S2-S90DOI: ( /j.ajkd ) Copyright © 2006 National Kidney Foundation, Inc. Terms and Conditions

11 American Journal of Kidney Diseases 2006 48, S2-S90DOI: (10. 1053/j
American Journal of Kidney Diseases  , S2-S90DOI: ( /j.ajkd ) Copyright © 2006 National Kidney Foundation, Inc. Terms and Conditions

12 American Journal of Kidney Diseases 2006 48, S2-S90DOI: (10. 1053/j
American Journal of Kidney Diseases  , S2-S90DOI: ( /j.ajkd ) Copyright © 2006 National Kidney Foundation, Inc. Terms and Conditions

13 American Journal of Kidney Diseases 2006 48, S2-S90DOI: (10. 1053/j
American Journal of Kidney Diseases  , S2-S90DOI: ( /j.ajkd ) Copyright © 2006 National Kidney Foundation, Inc. Terms and Conditions

14 American Journal of Kidney Diseases 2006 48, S2-S90DOI: (10. 1053/j
American Journal of Kidney Diseases  , S2-S90DOI: ( /j.ajkd ) Copyright © 2006 National Kidney Foundation, Inc. Terms and Conditions

15 American Journal of Kidney Diseases 2006 48, S2-S90DOI: (10. 1053/j
American Journal of Kidney Diseases  , S2-S90DOI: ( /j.ajkd ) Copyright © 2006 National Kidney Foundation, Inc. Terms and Conditions

16 American Journal of Kidney Diseases 2006 48, S2-S90DOI: (10. 1053/j
American Journal of Kidney Diseases  , S2-S90DOI: ( /j.ajkd ) Copyright © 2006 National Kidney Foundation, Inc. Terms and Conditions

17 American Journal of Kidney Diseases 2006 48, S2-S90DOI: (10. 1053/j
American Journal of Kidney Diseases  , S2-S90DOI: ( /j.ajkd ) Copyright © 2006 National Kidney Foundation, Inc. Terms and Conditions

18 American Journal of Kidney Diseases 2006 48, S2-S90DOI: (10. 1053/j
American Journal of Kidney Diseases  , S2-S90DOI: ( /j.ajkd ) Copyright © 2006 National Kidney Foundation, Inc. Terms and Conditions

19 American Journal of Kidney Diseases 2006 48, S2-S90DOI: (10. 1053/j
American Journal of Kidney Diseases  , S2-S90DOI: ( /j.ajkd ) Copyright © 2006 National Kidney Foundation, Inc. Terms and Conditions

20 American Journal of Kidney Diseases 2006 48, S2-S90DOI: (10. 1053/j
American Journal of Kidney Diseases  , S2-S90DOI: ( /j.ajkd ) Copyright © 2006 National Kidney Foundation, Inc. Terms and Conditions

21 American Journal of Kidney Diseases 2006 48, S2-S90DOI: (10. 1053/j
American Journal of Kidney Diseases  , S2-S90DOI: ( /j.ajkd ) Copyright © 2006 National Kidney Foundation, Inc. Terms and Conditions

22 Table American Journal of Kidney Diseases  , S2-S90DOI: ( /j.ajkd ) Copyright © 2006 National Kidney Foundation, Inc. Terms and Conditions

23 American Journal of Kidney Diseases 2006 48, S2-S90DOI: (10. 1053/j
American Journal of Kidney Diseases  , S2-S90DOI: ( /j.ajkd ) Copyright © 2006 National Kidney Foundation, Inc. Terms and Conditions

24 American Journal of Kidney Diseases 2006 48, S2-S90DOI: (10. 1053/j
American Journal of Kidney Diseases  , S2-S90DOI: ( /j.ajkd ) Copyright © 2006 National Kidney Foundation, Inc. Terms and Conditions

25 American Journal of Kidney Diseases 2006 48, S2-S90DOI: (10. 1053/j
American Journal of Kidney Diseases  , S2-S90DOI: ( /j.ajkd ) Copyright © 2006 National Kidney Foundation, Inc. Terms and Conditions

26 Table 18 American Journal of Kidney Diseases  , S2-S90DOI: ( /j.ajkd ) Copyright © 2006 National Kidney Foundation, Inc. Terms and Conditions

27 Table 19 American Journal of Kidney Diseases  , S2-S90DOI: ( /j.ajkd ) Copyright © 2006 National Kidney Foundation, Inc. Terms and Conditions


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