1. Correlated occupancies across FACT-bound regions.
Correlated occupancies across FACT-bound regions. (A) Heatmap representing Pearson's correlation between FACT subunits (SSRP1 and SUPT16) and other factors over the gene body area of all uniquely annotated protein-coding genes (n = 11,305). (B) Same as (A) but for promoter/active enhancer regions (n = 19,461) characterized by high H3K27ac and/or Pol II density. (C) Distribution of FACT and other factors (ChIP-seq tags indicated in blue) over the TSS of 11,305 unique RefSeq genes, sorted by H3K4me3 levels. Coinciding RNA expression levels are shown in red. (D) Distribution of several ChIP-seq datasets over a single gene (Egr1).
Constantine Mylonas, and Peter Tessarz LSA 2018;1:e
© 2018 Tessarz and Mylonas