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Volume 2, Issue 3, Pages 167-168 (September 2002)
Blocking oncogenes in malignant cells by RNA interference—New hope for a highly specific cancer treatment? Arndt Borkhardt Cancer Cell Volume 2, Issue 3, Pages (September 2002) DOI: /S (02)
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Figure 1 Different mechanisms of oncogene activation in human tumors
In cancer cells, proto-oncogenes have frequently been activated by various mechanisms, producing oncogenes that act in a dominant fashion. In epithelial tumors, point mutations are predominant whereas hematological malignancies often show gene fusions that result from chromosomal translocations. Cancer Cell 2002 2, DOI: ( /S (02) )
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