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The Single-Cell Yin and Yang of Live Imaging and Transcriptomics

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Presentation on theme: "The Single-Cell Yin and Yang of Live Imaging and Transcriptomics"— Presentation transcript:

1 The Single-Cell Yin and Yang of Live Imaging and Transcriptomics
Michael Tsabar, Galit Lahav  Cell Systems  Volume 4, Issue 4, Pages (April 2017) DOI: /j.cels Copyright © 2017 Elsevier Inc. Terms and Conditions

2 Figure 1 Yin and Yang: Integrating Live Imaging with Transcriptomics to Make Single Cells Whole Combining live-cell imaging with single-cell RNA-seq allows researchers to develop a comprehensive understanding of cellular responses. Here, Lane et al. capture single cells on a Fluidigm C1 microfluidic chip. Cells are tracked via live-cell imaging for several hours and then processed for single-cell RNA-seq. This allows the integration of a dynamic approach (live-cell imaging) with a static measurement (single-cell RNA-seq) while retaining the identity of the cells, yielding an unprecedented view of dynamic processes leading up to the time of RNA collection. Cell Systems 2017 4, DOI: ( /j.cels ) Copyright © 2017 Elsevier Inc. Terms and Conditions

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