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Alterations in Renal Microcirculation During Cardiopulmonary Bypass

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Presentation on theme: "Alterations in Renal Microcirculation During Cardiopulmonary Bypass"— Presentation transcript:

1 Alterations in Renal Microcirculation During Cardiopulmonary Bypass
Vivek L. Pathi, John Morrison, Alan MacPhaden, William Martin, Ann-Marie McQuiston, David J. Wheatley  The Annals of Thoracic Surgery  Volume 65, Issue 4, Pages (April 1998) DOI: /S (98)

2 Fig. 1 Glomerulus from group A. Well-filled capillaries with clear definition of glomerular anatomy. (AA = afferent arteriole; EA = efferent arteriole; GC = glomerular capillaries; PD = polar diameter.) The Annals of Thoracic Surgery  , DOI: ( /S (98) )

3 Fig. 2 Renal vascular resistance values for the four groups.
The Annals of Thoracic Surgery  , DOI: ( /S (98) )

4 Fig. 3 Corrosion cast of kidney in group A, revealing even filling of the entire renal cortex, with clear definition of the corticomedullary junction. (C = cortex; M = medulla.) The Annals of Thoracic Surgery  , DOI: ( /S (98) )

5 Fig. 4 Corrosion cast of kidney from group D revealing a lack of filling of the superficial cortex. The Annals of Thoracic Surgery  , DOI: ( /S (98) )

6 Fig. 5 Glomerulus from group B. Smaller glomerulus with narrowed capillaries suggesting diversion of flow through alternative channels. The Annals of Thoracic Surgery  , DOI: ( /S (98) )

7 Fig. 6 Glomerulus from group C. Severe reduction in size of glomerulus with complete loss of functional unit. These act as shunts between afferent and efferent arteriolar systems. The Annals of Thoracic Surgery  , DOI: ( /S (98) )

8 Fig. 7 Glomerulus from group D. Some recovery of anatomy of the functional unit, although shunting of blood past the nephrons is still evident. Narrowing of the capillaries and increase in intercapillary spaces suggest interstitial edema. The Annals of Thoracic Surgery  , DOI: ( /S (98) )


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