1. Whole-Genome Sequencing in Healthy People
Noralane M. Lindor, MD, Stephen N. Thibodeau, PhD, Wylie Burke, MD, PhD 
Mayo Clinic Proceedings 
Volume 92, Issue 1, Pages (January 2017)
DOI: /j.mayocp
Copyright © 2016 Mayo Foundation for Medical Education and Research Terms and Conditions

2. Figure 1
Overview of the next-generation DNA sequencing workflow. CNV = copy number variant; Indels = insertions and deletions; SNV = single nucleotide variant; SV = structural variant.
Adapted from Gut,6 with permission.
Mayo Clinic Proceedings  , DOI: ( /j.mayocp )
Copyright © 2016 Mayo Foundation for Medical Education and Research Terms and Conditions

3. Figure 2
Clinically relevant pharmacogenomic variants are not uncommon in the general population. FDA = Food and Drug Administration.
Data from Nature,19 with permission.
Mayo Clinic Proceedings  , DOI: ( /j.mayocp )
Copyright © 2016 Mayo Foundation for Medical Education and Research Terms and Conditions

4. Figure 3 Genomic sequencing trajectory from the 1990s to the present.
Mayo Clinic Proceedings  , DOI: ( /j.mayocp )
Copyright © 2016 Mayo Foundation for Medical Education and Research Terms and Conditions