1. Plasma active glucagon-like peptide-1 (GLP-1) response in patients with type  2 diabetes during the liquid high-fat meal test at baseline, 12 weeks and 24 weeks.
Plasma active glucagon-like peptide-1 (GLP-1) response in patients with type  2 diabetes during the liquid high-fat meal test at baseline, 12 weeks and 24 weeks. (A) Plasma levels of active GLP-1 in the ursodeoxycholic acid (UDCA)-first group (n=8, left panel) and (B) sitagliptin-first group (n=8, right panel). Each plot represents the mean±SE of the mean. White circles, baseline; black circles, UDCA alone; black triangle, sitagliptin alone; white square, combination of UDCA and sitagliptin. *P value for the intragroup comparison (baseline vs 12 weeks). (C) Area under the curve (AUC) of active GLP-1 concentrations (n=8/group). All data are presented as median with IQR (box) and total range (whiskers). Center lines show the medians, box limits indicate the 25th and 75th percentiles, whiskers extend 1.5×IQR from the 25th and 75th percentiles, and data points are plotted as dots.
Kosuke Robert Shima et al. BMJ Open Diab Res Care 2018;6:e000469
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