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Inflammation But Not Biliary Obstruction Is Associated With Carbohydrate Antigen Levels in Patients With Primary Sclerosing Cholangitis Andreas Wannhoff, Christian Rupp, Kilian Friedrich, Maik Brune, Johannes Knierim, Christa Flechtenmacher, Peter Sauer, Wolfgang Stremmel, Johannes R. Hov, Peter Schirmacher, Karl Heinz Weiss, Daniel N. Gotthardt Clinical Gastroenterology and Hepatology Volume 13, Issue 13, Pages (December 2015) DOI: /j.cgh Copyright © 2015 AGA Institute Terms and Conditions
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Figure 1 Selection of study population. Flow chart representing the recruitment of study patients, including those excluded from the study. Clinical Gastroenterology and Hepatology , DOI: ( /j.cgh ) Copyright © 2015 AGA Institute Terms and Conditions
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Figure 2 Correlation between CA19-9 and laboratory values. Correlation between CA19-9 and laboratory values indicating cholestasis (A, ALP, γGT, and total bilirubin), and (B) transaminase levels and (C) markers of inflammation. All x-axes are cut-off at a CA19-9 level of 500 U/mL. *P < .05, **P < .01, ***P < .001. Clinical Gastroenterology and Hepatology , DOI: ( /j.cgh ) Copyright © 2015 AGA Institute Terms and Conditions
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Figure 3 Influence of DS and SBC on CA19-9 level. (A) The influence of SBC on CA19-9 levels is more dominant in comparison with the influence of cholestasis. For both cholestasis, as indicated by the endoscopic finding of a (B) DS, and (C) SBC, there is a significant influence of the FUT2/3 genotype on the CA19-9 level. *P < .05, **P < .01, ***P < .001. Clinical Gastroenterology and Hepatology , DOI: ( /j.cgh ) Copyright © 2015 AGA Institute Terms and Conditions
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