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Re-emergence of anti-topoisomerase I antibody with exacerbated development of skin sclerosis in a patient with systemic sclerosis  Yasuhito Hamaguchi,

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Presentation on theme: "Re-emergence of anti-topoisomerase I antibody with exacerbated development of skin sclerosis in a patient with systemic sclerosis  Yasuhito Hamaguchi,"— Presentation transcript:

1 Re-emergence of anti-topoisomerase I antibody with exacerbated development of skin sclerosis in a patient with systemic sclerosis  Yasuhito Hamaguchi, MD, PhD, Manabu Fujimoto, MD, Minoru Hasegawa, MD, PhD, Takashi Matsushita, MD, PhD, Kazuhiko Takehara, MD, PhD  Journal of the American Academy of Dermatology  Volume 62, Issue 1, Pages (January 2010) DOI: /j.jaad Copyright © 2009 American Academy of Dermatology, Inc. Terms and Conditions

2 Fig 1 Serial changes in serum anti–topo I antibody levels in our patient who showed a decrease in antibody level in parallel with significant improvement in MRSS. Bold lines indicate MRSS; dashed lines indicate anti–topo I antibody levels determined by enzyme-linked immunosorbent assay. Journal of the American Academy of Dermatology  , DOI: ( /j.jaad ) Copyright © 2009 American Academy of Dermatology, Inc. Terms and Conditions

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