Presentation is loading. Please wait.

Presentation is loading. Please wait.

Increased Copy Number of the Interleukin-6 Receptor Gene Is Associated with Adverse Survival in Multiple Myeloma Patients Treated with Autologous Stem.

Similar presentations


Presentation on theme: "Increased Copy Number of the Interleukin-6 Receptor Gene Is Associated with Adverse Survival in Multiple Myeloma Patients Treated with Autologous Stem."— Presentation transcript:

1 Increased Copy Number of the Interleukin-6 Receptor Gene Is Associated with Adverse Survival in Multiple Myeloma Patients Treated with Autologous Stem Cell Transplantation  Seon Young Kim, Hyun Jung Min, Hyun Kyung Park, Bora Oh, Tae Young Kim, Cha Ja She, Sang Mee Hwang, Miyoung Kim, Hyun Kyung Kim, Inho Kim, Sung-Soo Yoon, Seonyang Park, Byoung Kook Kim, Jae Hoon Lee, Dong Soon Lee  Biology of Blood and Marrow Transplantation  Volume 17, Issue 6, Pages (June 2011) DOI: /j.bbmt Copyright © 2011 American Society for Blood and Marrow Transplantation Terms and Conditions

2 Figure 1 A Kaplan-Meier analysis of OS is displayed in relation to (A) increased IL-6R copy number, (B) t(14q32), (C) t(4;14), (D) t(11;14), (E) RB1 deletion, and (F) TP53 deletion. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2011 American Society for Blood and Marrow Transplantation Terms and Conditions

3 Figure 2 Survival according to the mean IL-6R gene copy per plasma cell. (A) PFS and (B) OS in patients who underwent ASCT. (C) PFS and (D) OS in patients that received chemotherapy only. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2011 American Society for Blood and Marrow Transplantation Terms and Conditions

4 Figure 3 A Kaplan-Meier analysis of OS among patients treated with autologous stem cell transplantation (ASCT) is displayed (A) according to t(4;14) and the copy number change of IL-6R and (B) according to the β2-microglobulin (β2-MG) level and the copy number change of IL-6R. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2011 American Society for Blood and Marrow Transplantation Terms and Conditions


Download ppt "Increased Copy Number of the Interleukin-6 Receptor Gene Is Associated with Adverse Survival in Multiple Myeloma Patients Treated with Autologous Stem."

Similar presentations


Ads by Google