1. A Rarity in a Common Disease: Thyroid Paraganglioma
Jutarat Sangtian, MD, Maria Rae Evasovich, MD, Tasma Harindhanavudhi, MD 
The American Journal of Medicine 
Volume 130, Issue 4, Pages e133-e135 (April 2017)
DOI: /j.amjmed
Copyright © 2016 Elsevier Inc. Terms and Conditions

2. Figure 1
Thyroid ultrasound demonstrated a large complex nodule measuring 6.6 × 4.5 × 3.3 cm with central internal blood flow that occupied almost the entire left thyroid lobe.
The American Journal of Medicine  , e133-e135DOI: ( /j.amjmed )
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3. Figure 2
Fine-needle aspiration of the left solitary thyroid nodule revealed groups of benign epithelial cells and colloid in the background (Wright stain).
The American Journal of Medicine  , e133-e135DOI: ( /j.amjmed )
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4. Figure 3
Hematoxylin & eosin-stained section of the specimen revealed tumor arranged in organoid vascularized pattern, with Zellballen architecture comprised of central cells with often highly pleomorphic enlarged nuclei and abundant eosinophilic and vacuolized cytoplasm, surrounded by spindle sustentacular cells (20× magnification).
The American Journal of Medicine  , e133-e135DOI: ( /j.amjmed )
Copyright © 2016 Elsevier Inc. Terms and Conditions

5. Figure 4
Immunohistochemical stains of the specimen revealed positivity of chromogranin (label A) and synaptophysin (label B) in organoid neoplastic cells and S100 (label C) highlighted sustentacular cells.
The American Journal of Medicine  , e133-e135DOI: ( /j.amjmed )
Copyright © 2016 Elsevier Inc. Terms and Conditions