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Analysis of superantigenic toxin Vβ T-cell signatures produced during cases of staphylococcal toxic shock syndrome and septic shock  T. Ferry, D. Thomas,

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Presentation on theme: "Analysis of superantigenic toxin Vβ T-cell signatures produced during cases of staphylococcal toxic shock syndrome and septic shock  T. Ferry, D. Thomas,"— Presentation transcript:

1 Analysis of superantigenic toxin Vβ T-cell signatures produced during cases of staphylococcal toxic shock syndrome and septic shock  T. Ferry, D. Thomas, T. Perpoint, G. Lina, G. Monneret, I. Mohammedi, C. Chidiac, D. Peyramond, F. Vandenesch, J. Etienne  Clinical Microbiology and Infection  Volume 14, Issue 6, Pages (June 2008) DOI: /j x Copyright © 2008 European Society of Clinical Infectious Diseases Terms and Conditions

2 Fig. 1 Vβ repertoire of two patients with menstrual toxic shock syndrome (TSS), two patients with non-menstrual TSS, and two patients with septic shock. The data reveal a superantigenic toxin Vβ signature during TSS, but not during septic shock. *, Vβ expansion of more than two standard deviations above that of the controls; *, Vβ expansion of less than two standard deviations above that of the controls, but with >1.5-fold variation of a Vβ subset between two time-points. NA, data not available; TSST-1, toxic shock syndrome toxin-1; SE, staphylococcal enterotoxin. Clinical Microbiology and Infection  , DOI: ( /j x) Copyright © 2008 European Society of Clinical Infectious Diseases Terms and Conditions


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