1. An FXR Agonist Reduces Bile Acid Synthesis Independently of Increases in FGF19 in Healthy Volunteers 
Amani Al-Khaifi, Mats Rudling, Bo Angelin 
Gastroenterology 
Volume 155, Issue 4, Pages (October 2018)
DOI: /j.gastro
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2. Gastroenterology 2018 155, 1012-1016DOI: (10. 1053/j. gastro. 2018. 06
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3. Figure 1
Serum total and individual BAs, FGF19, and C4 in placebo group (A–C). Temporal responses (% of baseline) for serum total BAs, FGF19, and C4 (D, E, F) and serum lathosterol, total cholesterol, and triglycerides (G, H, I) for all subjects. Mean ± SEM. Arrows indicate meal (green) and drug (yellow) intake.
Gastroenterology  , DOI: ( /j.gastro )
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4. Figure 2
Temporal responses (% of baseline) for serum FGF19 and C4 in all Px-102–treated groups. Mean ± SEM. Arrows indicate meal (green) and drug (yellow) intake. Significance of difference vs placebo group determined using 2-way analysis of variance with post hoc Dunnett's test. *P < .05; **P < .01; ***P < .001; ****P <
Gastroenterology  , DOI: ( /j.gastro )
Copyright © 2018 AGA Institute Terms and Conditions