1. Genetic Pedigrees

2. Creating a Pedigree H h H h hh H ? H ?
Key
H = Healthy
h = PKU H h H h hh H ? H ?
1) Manny and Rosa are married and both are healthy.
2) They have 3 children.
3) Their oldest child, Jacob, has a recessive disorder called PKU.
4) Their middle child Erica and their youngest Matthew are healthy.
If healthy is dominant to PKU, fill in the missing genotypes. (start with what you know)

3. The Next Generation
Key
H = Healthy
h = PKU H h H h H ? hh
5) Erica meets Moe at college and the two become married.
6) Erica and Moe have 2 daughters.
7) Their youngest daughter Jamie shows signs of PKU while Amy does not.
Fill in the genotypes of the four individuals. (start with what you know)

4. Fill in the X-linked Pedigree

5. Sickle cell anemia (recessive) pedigreeHh hh H? hh Hh hh Hh Hh hh Hh Hh H?
Key
H = Healthy
h = Sickle cell anemia H?