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Confirmation of pool data with isogenic culture

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Presentation on theme: "Confirmation of pool data with isogenic culture"— Presentation transcript:

1 Confirmation of pool data with isogenic culture
Confirmation of pool data with isogenic culture Multiple strains that displayed enhanced or diminished growth (green and red, respectively) in the pool screen in doxorubicin, FK506, NaCl, or atorvastatin, as well as several control strains (black), were grown in isogenic cultures. Relative growth values were calculated for either 300 OD measurements (doxorubicin) or 150 OD measurements (FK506, atorvastatin, and NaCl) and compared to ratios derived from the pooled experiment.Several PCA strains (indicated in the legend) with enhanced or diminished growth rates identified in the pool screen in NaCl, atorvastatin, hydrogen peroxide, and doxorubicin were grown in selective media in the presence of multiple concentrations of the four agents (indicated on the x‐axis of each plot). The strains that were identified in the pool assay in each condition are marked with an asterisk. Growth relative to that in the standard environment is indicated on the y‐axis. Albi Celaj et al. Mol Syst Biol 2017;13:934 © as stated in the article, figure or figure legend

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