1. Topical Agents for the Management of Musculoskeletal Pain
Steven P. Stanos, DO 
Journal of Pain and Symptom Management 
Volume 33, Issue 3, Pages (March 2007)
DOI: /j.jpainsymman
Copyright © 2007 U.S. Cancer Pain Relief Committee Terms and Conditions

2. Fig. 1
Anatomy and physiology of the skin with the potential targets or sites of action of selected analgesics. Adapted from Ref. 14.
Journal of Pain and Symptom Management  , DOI: ( /j.jpainsymman )
Copyright © 2007 U.S. Cancer Pain Relief Committee Terms and Conditions

3. Fig. 2
TRP family receptors and their thermosensitivity (adapted from Ref. 69).
Journal of Pain and Symptom Management  , DOI: ( /j.jpainsymman )
Copyright © 2007 U.S. Cancer Pain Relief Committee Terms and Conditions

4. Fig. 3
Acute activation of the TRPV1 receptor leads to local intracellular calcium signals and the sensation of heat or burning pain. TRPV-transient receptor potential vanilloid. Reprinted with permission from Ref. 6.
Journal of Pain and Symptom Management  , DOI: ( /j.jpainsymman )
Copyright © 2007 U.S. Cancer Pain Relief Committee Terms and Conditions