1. Genetic Map of Drosophila
Fig. 5-14

2. Pairing of Homologous Chromosomes
Fig. 2-13, 2-14

4. Crossing Over Occurs Between DNA of Homologous Chromosomes
Paternal
Paired
Homologous
Chromosomes
Maternal

5. Fig. 2-8

6. Drosophila melanogaster (Fruit Fly)
Phenotypes
eye color
body color
wing shape
antenna length
bristle pattern

7. Single Crossover (SCO)
Paternal
Paired
Homologous
Chromosomes
Maternal

8. Double Crossover (DCO)
Paternal
Paired
Homologous
Chromosomes
Maternal
DCO Products

9. Pedigree for ABO Blood Group and Nail-Patella Syndrome

10. HIV-1 Structure
(Gp120)

11. HIV Infection Pathway HIV-1 Extra-cellular Space Gp120 Membrane CCR5
Cytosol
Protein encoded
By CCR5-1 allele
(CCR5-1 / CCR5-1 or CCR5-1 / CCR5-∆32)

12. CCR5 RFLP
CCR5-1
CCR5-∆32

13. CCR5 Genotype Analysis
Fig. 25-3

14. CCR5-∆32 Allele Frequency
Fig. 25-4

15. Assumptions of the Hardy-Weinberg Equation
Individuals of all genotypes have equal rates of survival and
reproductive success (no selection).
No new alleles are created or converted from one allele to
another by mutation.
Individuals do not migrate into or out of the population
(no gene flow).
The population is infinitely large (no genetic drift).
Individuals in the population mate randomly (no inbreeding)
Page

16. Changes in CCR5-∆32 Allele Frequency
Fig. 25-8

17. Effect of Selection on Allele Frequency
Fig. 25-7

18. Pedigree Showing First Cousin Mating

19. Organization of Human Genome
(~ 50 kbp)
Genes comprise ~ 5% of genome
Repeated DNA comprises ~ 50% of genome (purple blocks)
VNTR (Variable Number Tandem Repeat)
STR (Short Tandem Repeat)
Unique (“junk”) DNA comprises the rest
Fig. 20-8
Pg. 494

20. Chromosome 7
STR-D
STR-C
STR-B
STR-E
STR-F
STR-A

21. 7M 7P 7M 7P GTCTAG GTCTAG GTCTAG CAGATC CAGATC CAGATC
STR-D
STR-C
STR-B
STR-E
STR-F
STR-A 7M 7P 7M
GTCTAG GTCTAG GTCTAG
CAGATC CAGATC CAGATC
GTCTAG GTCTAG GTCTAG GTCTAG
CAGATC CAGATC CAGATC CAGATC 7P

22. RFLP Analysis of VNTR Locus
Fig

23. Fig