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Introduction to CNS pharmacology

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Presentation on theme: "Introduction to CNS pharmacology"— Presentation transcript:

1 Introduction to CNS pharmacology
By S.Bohlooli, PhD

2 Ion channels & neurotransmitter receptors
Voltage gated channels Ligand gated channels Ionotropic receptors Metabotropic receptors Membrane delimited Diffusible second messenger

3

4 The synapse & synaptic potentials
Excitatory Excitatory post-synaptic potential (EPSP) Ionotropic receptor Inhibitory Inhibitory post-synaptic potential (IPSP) Presynaptic inhibition

5

6 Site of drug action

7 Central neurotransmitters
Amino acids Neutral amino acids Acidic amino acids Acetylcholine Monoamines Dopamine Norepinephrine 5-hydroxytryptamine Peptides Nitric oxide endocananbiniods

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