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Photo-induced erythema multiforme associated with vandetanib administration  Dolores Caro-Gutiérrez, MD, Maria Uxúa Floristán Muruzábal, MD, Enrique Gómez.

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Presentation on theme: "Photo-induced erythema multiforme associated with vandetanib administration  Dolores Caro-Gutiérrez, MD, Maria Uxúa Floristán Muruzábal, MD, Enrique Gómez."— Presentation transcript:

1 Photo-induced erythema multiforme associated with vandetanib administration 
Dolores Caro-Gutiérrez, MD, Maria Uxúa Floristán Muruzábal, MD, Enrique Gómez de la Fuente, MD, Ana Pampín Franco, MD, José Luis López Estebaranz, MD  Journal of the American Academy of Dermatology  Volume 71, Issue 4, Pages e142-e144 (October 2014) DOI: /j.jaad Copyright © 2014 American Academy of Dermatology, Inc. Terms and Conditions

2 Fig 1 Photo-induced erythema multiforme. A and B, Targetoid lesions on both hands. C, Superficial perivascular and interstitial dermatitis with eosinophils, interface dermatitis of vacuolar type with abundant degenerated keratinocytes, and mild spongiosis. (C, Hematoxylin-eosin stain; original magnification: ×200.) Journal of the American Academy of Dermatology  , e142-e144DOI: ( /j.jaad ) Copyright © 2014 American Academy of Dermatology, Inc. Terms and Conditions

3 Fig 2 Photo-test during vandetanib intake showed a diminished minimal erythema dose (MED) after ultraviolet (UV) A exposure (<1 J/cm2) (second row). MED after UVB exposure (first row). Journal of the American Academy of Dermatology  , e142-e144DOI: ( /j.jaad ) Copyright © 2014 American Academy of Dermatology, Inc. Terms and Conditions


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