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Ergocalciferol and Cholecalciferol in CKD
Sagar U. Nigwekar, MD, Ishir Bhan, MD, MPH, Ravi Thadhani, MD, MPH American Journal of Kidney Diseases Volume 60, Issue 1, Pages (July 2012) DOI: /j.ajkd Copyright © 2012 National Kidney Foundation, Inc. Terms and Conditions
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Figure 1 Chemical structures of vitamin D compounds.
American Journal of Kidney Diseases , DOI: ( /j.ajkd ) Copyright © 2012 National Kidney Foundation, Inc. Terms and Conditions
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Figure 2 Metabolism of vitamin D. Endocrine and autocrine/intracrine actions of vitamin D. In addition to the traditional endocrine actions of 1,25(OH)2D (1,25-dihydroxyvitamin D) on the parathyroid glands and intestinal calcium and phosphate transport, peripheral conversion of 25(OH)D (25-hydroxyvitamin D) to 1,25(OH)2D is likely to be important in mediating autocrine and intracrine activities, particularly in the immune system. Abbreviations: Ca/PO4, calcium/phosphate; CKD, chronic kidney disease; PTH, parathyroid hormone. Reproduced from Bhan et al with permission of Wiley Periodicals, Inc.40 American Journal of Kidney Diseases , DOI: ( /j.ajkd ) Copyright © 2012 National Kidney Foundation, Inc. Terms and Conditions
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