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Fig. 3. Structure of ALS-associated RNA binding proteins.

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Presentation on theme: "Fig. 3. Structure of ALS-associated RNA binding proteins."— Presentation transcript:

1 Fig. 3. Structure of ALS-associated RNA binding proteins.
Structure of ALS-associated RNA binding proteins. The glycine/serine-tyrosine-glycine/serine (G/S-Y-G/S) motif and the arginine/glycine/glycine repeat (RGG) motif, which are predicted to have prion-like properties, are shown. Thick black line shows the prion-like domain (PrLD) and the amino acid positions that it occupies. Mutations identified in ALS/FTD, distal myopathy, or both diseases are shown by red, blue, and green tick marks, respectively. Seven of the ALS-related RNA binding proteins contain a PrLD, but Matrin 3 does not. RRM, RNA recognition motif; GRD, glycine-rich domain. Daisuke Ito et al., Sci Transl Med 2017;9:eaah5436 Published by AAAS

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