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High specificity and sensitivity of NRAS Q61R immunohistochemistry (IHC) in melanomas
Pierre-Alexandre Just, MD, PhD, Christelle Pouliquen, MD, Anne Audebourg, Dr-Ing, Sara Laurent-Roussel, MD, Agnès Carlotti, MD, Nicolas Dupin, MD, PhD, Marie-Cécile Vacher-Lavenu, MD, PhD, Michel Vidaud, PharmD, PhD, Benoît Terris, MD, PhD, Eric Pasmant, PharmD, PhD Journal of the American Academy of Dermatology Volume 74, Issue 3, Pages (March 2016) DOI: /j.jaad Copyright © 2015 American Academy of Dermatology, Inc. Terms and Conditions
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Fig 1 A, Melanoma with NRAS Q61R mutation: anti-NRAS Q61R immunohistochemistry (IHC). Note strong and diffuse cytoplasmic staining of tumor cells and the nonspecific staining of endothelial cells. B, Melanoma without NRAS Q61R mutation: anti-NRAS Q61R IHC. Note the nonspecific staining of endothelial cells and the absence of staining in tumor cells. Journal of the American Academy of Dermatology , DOI: ( /j.jaad ) Copyright © 2015 American Academy of Dermatology, Inc. Terms and Conditions
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