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Volume 42, Issue 4, Pages (April 2005)

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Presentation on theme: "Volume 42, Issue 4, Pages (April 2005)"— Presentation transcript:

1 Volume 42, Issue 4, Pages 585-591 (April 2005)
Heme oxygenase-1 levels and oxidative stress-related parameters in non-alcoholic fatty liver disease patients  Lucia Malaguarnera, Roberto Madeddu, Elisabetta Palio, Nicolò Arena, Mariano Malaguarnera  Journal of Hepatology  Volume 42, Issue 4, Pages (April 2005) DOI: /j.jhep Copyright © 2005 European Association for the Study of the Liver Terms and Conditions

2 Fig. 1 Quantification of HO-1 mRNA levels by Real Time PCR in normal subjects, in simple steatosis and NASH patients. Levels of HO-1 mRNA are normalized to GAPDH. mRNA levels are expressed as 2−ΔΔct value. Journal of Hepatology  , DOI: ( /j.jhep ) Copyright © 2005 European Association for the Study of the Liver Terms and Conditions

3 Fig. 2 Correlation between ferritin and HO-1 levels: (A) normal subjects; (B) simple steatosis; (C) NASH patients with different grades of severity: grade 0 (●), grade 1 (), grade 2 (), grade 3 (), grade 4 (). Results in the different groups are expressed as nanomol ferritin/g liver. [This figure appears in colour on the web.] Journal of Hepatology  , DOI: ( /j.jhep ) Copyright © 2005 European Association for the Study of the Liver Terms and Conditions

4 Fig. 3 Correlation between lipid peroxidation and HO-1 levels: (A) normal subjects; (B) simple steatosis; (C) NASH patients with different grades of severity: grade 0 (●), grade 1 (), grade 2 (), grade 3 (), grade 4 (). Results in the different groups are expressed as MDA in ηmol per g of liver. [This figure appears in colour on the web.] Journal of Hepatology  , DOI: ( /j.jhep ) Copyright © 2005 European Association for the Study of the Liver Terms and Conditions

5 Fig. 4 Correlation between GSH and HO-1 levels: (A) normal subjects; (B) simple steatosis; (C) NASH patients with different grades of severity: grade 0 (●), grade 1 (), grade 2 (), grade 3 (), grade 4 (). Results are expressed as μmolGSH/g liver. [This figure appears in colour on the web.] Journal of Hepatology  , DOI: ( /j.jhep ) Copyright © 2005 European Association for the Study of the Liver Terms and Conditions


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