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Clinical Recognition and Treatment of Levodopa-Induced Dyskinesia

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Presentation on theme: "Clinical Recognition and Treatment of Levodopa-Induced Dyskinesia"— Presentation transcript:

1 Clinical Recognition and Treatment of Levodopa-Induced Dyskinesia

2

3 Levodopa-Induced Dyskinesia Introduction

4 Prevalence of Dyskinesia

5 Videos: Disordered Movement Types

6 Fluctuations in Dopamine Levels

7 Dysregulation of Dopamine Leading to the Development of Dyskinesia

8 Effects of AEs on Patient Quality of Life

9 Patient-Rated Impairment in Quality of Life

10 Rating Scales Used to Assess Dyskinesia

11 Approaches to Levodopa-Induced Dyskinesia Management

12 Amantadine IR

13 Amantadine ER Overview of Clinical Studies

14 Primary Endpoint: UDysRS Results Over Time EASE LID and EASE LID 3

15 Key Secondary Endpoints: Home Diary Data EASE LID and EASE LID 3

16 Most Common AEs and Reasons for Treatment Discontinuation Amantadine ER

17 Additional Approaches

18 Concluding Remarks

19 Abbreviations


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