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Published byΆγνη Στεφανόπουλος Modified over 6 years ago
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Cell Biology: Microtubule Collisions to the Rescue
Melissa K. Gardner Current Biology Volume 26, Issue 24, Pages R1287-R1289 (December 2016) DOI: /j.cub Copyright © 2016 Elsevier Ltd Terms and Conditions
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Figure 1 Microtubule self-repair and rescue.
Top: Growing microtubules may acquire lattice damage during growth (blue arrow), potentially as a result of collisions with other microtubules. Middle: GTP-tubulin subunits may then ‘fill in’ the lattice defect, generating an island of GTP-tubulin within the microtubule lattice (red GTP-tubulin subunits at blue arrow). Bottom: After a stochastic catastrophe event, a GTP-tubulin island may slow microtubule shortening, and thus increase the probability of a rescue event that originates at the island. Current Biology , R1287-R1289DOI: ( /j.cub ) Copyright © 2016 Elsevier Ltd Terms and Conditions
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