1. Potato Genome Project Structural Genomics 2.Functional Genomics
Generation of a comprehensive genomic resource of Solanaceae resistance (R) gene sequences of wild potato, tomato and pepper genomes (the SOLAR database)
2.Functional Genomics
Generation of a comprehensive functional genomic resource composed of expression profiles of significant points in growth, development and response to abiotic and biotic stresses, and a set of functionally defined genes identified through virus-induced gene silencing to be involved in host response to pathogens
3.Outreach
A training program for high school and college students to teach applications of bioinformatics and data mining for marker development for potato breeding for crop improvement

2. Synteny between Solanaceae Genomes1 2 3 4 5 6 7 8 9 10 11 12
The Solanaceae share highly conserved genomes
Chromosome number and organization
Genome sequence
Sequence and function of gene location and
resistance hotspot location
Potato 1 2 3 4 5 6 7 8 9 10 11 12
Pepper 1 2 3 4 5 6 7 8 9 10 11 12
Tomato
Resistance hotspots

3. Chromosome 5 Resistance Region
Potato
R1, phyt3, Pi1,Nb, Rx2, Gpa, Grp
GP21
GP179
Tomato
Bs4
GP21
GP179

4. S. demissum is an allo-hexaploid
Chromosome #5 5A 5B 5C
R1, phyt3, Pi1,Nb, Rx2, Gpa, Grp

5. S.demissum Chromosome 5 Resistance Region
R1, phyt3, Pi1, Nb, Rx2, Gpa, Grp
Chromosome #5
GP21
132D05
GP179
132D05
GP179
8~12 BACs per genome
~0.5Mb per genome R1
GP179
SPUD237
132D05S
GP21 A B C
Haplotype
Sd_Bs4 R1
Sd_Prf

6. S.demissum Chromosome 11 Resistance Region
Potato I
phyt3
L, cmv1, phyt3 I2
Tomato
Pepper
RMcl, Ry, Na, Sen1,
R3a, R3b, R5, R6, R7, R8, R9, R10, phyt7

7. S. demissum is hexaploid
Chromosome #11
11A
11B
11C
RMcl, Ry, Na, Sen1, N
R3a, R3b, R5, R6, R7, R8, R9, R10, phyt7

8. S.demissum Chromosome 11 Resistance Region
RMcl, Ry, Na, Sen1,
Chromosome #11
193I9R
56F6R
39E18F A
Haplotype B

9. S.demissum Chromosome 11 Resistance Region
R3a, R3b, R5, R6, R7, R8, R9, R10, phyt7
Chromosome #11
381T
373T
51S
11~16 BACs
1.5Mb
381T
373T
381T
TG105
373T A
Haplotype B C

10. S.demissum Chromosome 11 Resistance Region
R3a, R3b, R5, R6, R7, R8, R9, R10, phyt7
Chromosome #11
381T
373T
51S
12~16 BACs
~1.5Mb
373T
51S
GP185
373T
51S A
Haplotype B C

11. Distance tree for all I2/R3 homologues from the MLB locus6 5 1
100
100 4
100
100
100
100 3
0.1 substitution/site 2
GP185 region
GP250 region