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Volume 138, Issue 5, Pages e1 (May 2010)

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Presentation on theme: "Volume 138, Issue 5, Pages e1 (May 2010)"— Presentation transcript:

1 Volume 138, Issue 5, Pages 1854-1862.e1 (May 2010)
Aberrant DNA Methylation in Hereditary Nonpolyposis Colorectal Cancer Without Mismatch Repair Deficiency  Ajay Goel, Rosa M. Xicola, Thuy–Phuong Nguyen, Brian J. Doyle, Vanessa R. Sohn, Prathap Bandipalliam, Laura S. Rozek, Josep Reyes, Carmen Cordero, Francesc Balaguer, Antoni Castells, Rodrigo Jover, Montserrat Andreu, Sapna Syngal, C. Richard Boland, Xavier Llor  Gastroenterology  Volume 138, Issue 5, Pages e1 (May 2010) DOI: /j.gastro Copyright © 2010 AGA Institute Terms and Conditions

2 Figure 1 Pyrograms of methylation markers MLH1, NEUROG1, CACNAG1, RUNX3, SOCS1, and LINE-1. The black arrow points to the internal control cytosine residues that check for the adequacy of bisulfite treatment in the pyrosequencing reactions. No signal amplification was seen for the internal control, suggesting that 100% of the DNA samples used for various CIMP markers were converted satisfactorily by bisulfite treatment. Gastroenterology  , e1DOI: ( /j.gastro ) Copyright © 2010 AGA Institute Terms and Conditions


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