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A Genomewide Scan for Loci Involved in Attention-Deficit/Hyperactivity Disorder
Simon E. Fisher, Clyde Francks, James T. McCracken, James J. McGough, Angela J. Marlow, I. Laurence MacPhie, Dianne F. Newbury, Lori R. Crawford, Christina G.S. Palmer, J. Arthur Woodward, Melissa Del’Homme, Dennis P. Cantwell, Stanley F. Nelson, Anthony P. Monaco, Susan L. Smalley The American Journal of Human Genetics Volume 70, Issue 5, Pages (May 2002) DOI: /340112 Copyright © 2002 The American Society of Human Genetics Terms and Conditions
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Figure 1 LOD score plots from multipoint analyses of the whole genome in ASPs with ADHD. A, MLS analyses for “narrow” and “broad” diagnostic schemes. B, QTL analyses for total symptom count derived from clinical interview. Cumulative distance in Haldane centimorgans is displayed along the bottom, with chromosome numbers at the top. Peak LOD scores >1 are summarized in table 4. The American Journal of Human Genetics , DOI: ( /340112) Copyright © 2002 The American Society of Human Genetics Terms and Conditions
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Figure 2 Exclusion mapping of the whole genome in ADHD ASPs for a λs of 2. LOD score plots are shown under narrow and broad diagnostic schemes. Regions are excluded if they produce a LOD of <−2. See tables 5 and 6 for more details. Cumulative distance in Haldane centimorgans is displayed along the bottom, with chromosome numbers at the top. The American Journal of Human Genetics , DOI: ( /340112) Copyright © 2002 The American Society of Human Genetics Terms and Conditions
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