1. Glycosaminoglycan Therapy for Bladder Diseases: Emerging New Treatments 
Pier Francesco Bassi, Elisabetta Costantini, Steve Foley, Stefano Palea 
European Urology Supplements 
Volume 10, Issue 6, Pages (October 2011)
DOI: /j.eursup
Copyright © 2011 European Association of Urology Terms and Conditions

2. Fig. 1
Experimental protocol for repeated treatment with sodium hyaluronate–chondroitin sulfate (HA-CS) in an animal bladder model [25].
KCl=potassium chloride; PS=protamine sulfate; s.c.=subcutaneous.
European Urology Supplements  , DOI: ( /j.eursup )
Copyright © 2011 European Association of Urology Terms and Conditions

3. Fig. 2
Urinary function results: bladder capacity (BC), threshold pressure (ThP), micturition pressure (MP), and bladder compliance with instillations of sodium hyaluronate–chondroitin sulfate (HA-CS) in the rat bladder model [25].
ANOVA=analysis of variance; KCl=potassium chloride; NaCl=sodium chloride; PS=protamine sulfate.
European Urology Supplements  , DOI: ( /j.eursup )
Copyright © 2011 European Association of Urology Terms and Conditions

4. Fig. 3
Kaplan-Meier plot of time to recurrence of infection in patients with recurrent urinary tract infections receiving intravesical sodium hyaluronate–chondroitin sulfate (HA/CS) or placebo. Reproduced with permission from Elsevier [32].
European Urology Supplements  , DOI: ( /j.eursup )
Copyright © 2011 European Association of Urology Terms and Conditions

5. Fig. 4
Urinary function parameters in patients with interstitial cystitis/painful bladder syndrome receiving intravesical sodium hyaluronate–chondroitin sulfate [2].
VAS=visual analog scale.
European Urology Supplements  , DOI: ( /j.eursup )
Copyright © 2011 European Association of Urology Terms and Conditions

6. Fig. 5
Quality-of-life assessments in patients with interstitial cystitis/painful bladder syndrome receiving intravesical sodium hyaluronate–chondroitin sulfate [2].
European Urology Supplements  , DOI: ( /j.eursup )
Copyright © 2011 European Association of Urology Terms and Conditions

7. Fig. 6
Efficacy of intravesical sodium hyaluronate–chondroitin sulfate in 17 patients with interstitial cystitis/painful bladder syndrome, treated in a district general hospital in Reading, UK [37].
PUF=Pelvic Pain and Urinary/Frequency (score); VA=visual analog (scale score).
European Urology Supplements  , DOI: ( /j.eursup )
Copyright © 2011 European Association of Urology Terms and Conditions