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This Month in Gastroenterology
Jan Tack, John M. Carethers Gastroenterology Volume 134, Issue 4, Pages (April 2008) DOI: /j.gastro Copyright © 2008 AGA Institute Terms and Conditions
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Figure 1 Progression rate of premalignant gastric lesions to gastric cancer in 92,250 patients with premalignant gastric lesions. Gastroenterology , DOI: ( /j.gastro ) Copyright © 2008 AGA Institute Terms and Conditions
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Figure 2 Receiver operating characteristic curves for the use of transient elastography in the diagnosis of cirrhosis, severe fibrosis, and significant fibrosis. Dots indicate 1-specificity and sensitivity of the single studies used in the meta-analysis. Gastroenterology , DOI: ( /j.gastro ) Copyright © 2008 AGA Institute Terms and Conditions
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Figure 3 Effects of hormonal substitution of hypophysectomized (Hx) rats on serum plant sterols. Hx-rats (n = 52) were substituted with growth hormone (GH, 1.5 mg/kg per day), l-thyroxine (T4, 42 μg/kg per day) and cortisone (C, 400 μg/kg per day) for 1 week. Intact rats (I; n = 5), and the Hx-control group received subcutaneous injections of NaCl. ¡P < .05 versus intact; *P < .01; **P < .001 versus Hx; ns, not significant. Gastroenterology , DOI: ( /j.gastro ) Copyright © 2008 AGA Institute Terms and Conditions
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Figure 4 Schematic representation of the bile salt export pump (BSEP) with location of mutations identified in the study. Schematic generated using TOPO2 software. Protein topology predicted by comparison with multidrug resistant protein MDR1. Transmembrane spans predicted to fit the accepted topology using TopPred II. Singly mutated residues represented as colored residues; founder/recurrent mutations indicted by arrows. For insertions/deletions the affected residue is indicated, for splice sites the adjacent amino acid. Color key: Blue, missense; red, stop; green, insertion/deletion; orange, splice site; black, several different mutations at a site; purple, Walker A, B, and ABC motifs. Gastroenterology , DOI: ( /j.gastro ) Copyright © 2008 AGA Institute Terms and Conditions
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