1. Cancer Images Database (caIMAGE)
Sohaib Waheed
Georgia Institute of Technology
June 29, 2006

2. What is caIMAGE ? an image portal/server
developed by the National Cancer Institute (NCI)
allows researchers to search and submit images with annotations
a public service to foster the rapid dissemination of information

3. You may not, however, caIMAGE You can browse distribute download
use
the data for noncommercial, scientific, and educational purposes
You may not, however,
distribute
modify
re-use
re-post
any materials for public or commercial purposes

4. caIMAGE – The portal
Search
Submit

5. caIMAGE - Searching The Simple Search Search parameters: Species
Organ/tissue
Diagnosis

6. caIMAGE - Searching Species
From the drop down menu choose one of the following species
Dog
Human
Macaca mulatta
(Rhesus monkey)
Mouse
Rat
Tamarin
(South american monkey)

7. caIMAGE - Searching Organ/Tissue
After selecting your species you can refine your search by selecting organ or tissue.
This opens a new window in which you can search by
Word/phrase
Data tree

8. Searching - caIMAGE Diagnosis
You can further refine you search by selecting diagnosis for your organ/tissue
Again you can search the diagnosis by both
Word/phrase
Data tree

9. caIMAGE – Search Results
Images and the relevant data with annotations
Image annotations may include
detailed description
species
gender
organ
diagnosis
staining
image dimension

10. caIMAGE - Images
Voila !!!
Image displayed in a popup window which has zooming and panning capabilities
You can download them by
 right click  save target as

11. caIMAGE – Advanced Search
Additional search tabs
By image
Image name / number
Staining
Specimen
With additional tabs like gender and mouse strain
Submitter
PI’s name
Institute name

12. caIMAGE – Image submission
Users may post images on the caIMAGE server
The images may already be published or public
All unpublished data is subject to copyright provisions

13. caIMAGE – Image submission
Before submitting you need to
certify that you are the author of the data
certify that the data was generated in your lab
certify that you have consulted with your institution’s technology development office
authorize the release of data

14. caIMAGE - Image submission
Guided online tutorial for image submission
Live demonstration

15. caIMAGE – Technical Details
The NCICB is investigating imaging technologies to facilitate efficient image retrieval and annotation integration
Imaging technologies include
JPEG 2000
DICOM 3 (Digital Imaging and Communications in Medicine)
Standard for the transferal of radiology images and other medical information
Image Content Servers provide a mechanism to speed image transmission and improve image quality

16. caIMAGE – Technical Details
To facilitate image sharing, a “minimal” set of image annotations are necessary
caIMAGE utilizes now anatomy and disease vocabularies served by the NCI Thesaurus
Image annotations should leverage existing standards and may be derived from used cases for image retrieval and analysis

17. caIMAGE - Architecture
Browser
Client
caIMAGE
Web Application Server
LizardTech Image Content Server
Network File System
CaIMAGE Database
Lizard Image Converter
Images
Image Annotations
Sid Files

18. caIMAGE - Conclusions The Good A step in the right direction
Common platform
Resource
Standardization
Annotations
Vocabulary
Image format

19. caIMAGE - Conclusions The Bad Nascent
Image quantity
Knowledge of annotations and vocabulary required
Needs improvement
architecture
data accessibility

20. caIMAGE
The End