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Immunoglobulin G4 Immunostaining of Gastric, Duodenal, or Colonic Biopsies Is Not Helpful for the Diagnosis of Autoimmune Pancreatitis Vinciane Rebours, Yann Le Baleur, Dominique Cazals–Hatem, Carmen Stefanescu, Olivia Hentic, Frédérique Maire, Yoram Bouhnik, Pierre Bedossa, Pascal Hammel, Philippe Ruszniewski, Philippe Lévy, Anne Couvelard Clinical Gastroenterology and Hepatology Volume 10, Issue 1, Pages (January 2012) DOI: /j.cgh Copyright © 2012 AGA Institute Terms and Conditions
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Figure 1 Colonic mucosa of a patient with ulcerative colitis without AIP. Mucosa contains abundant inflammatory infiltration with lymphoid aggregates (A, arrow). Plasma cells are numerous, highlighted by CD138 (B). Numerous IgG4-positive plasma cells are present in the lamina propria (C, D), which also contains a lymphoid aggregate (C, arrow). Seventeen IgG4 plasma cells are counted in this 0.2-mm2 area (D). (A) H&E staining; (B–D) immunohistochemistry, counterstained with hematoxylin. Clinical Gastroenterology and Hepatology , 91-94DOI: ( /j.cgh ) Copyright © 2012 AGA Institute Terms and Conditions
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