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Nanoparticulate Cancer-Starvation Therapy
Shutao Guo, Daniel S. Kohane Chem Volume 2, Issue 2, Pages (February 2017) DOI: /j.chempr Copyright © 2017 Elsevier Inc. Terms and Conditions
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Figure 1 Schematic Diagram of Mg2Si NPs Serving as an Intratumoral Deoxygenation Agent for Specific Cancer-Starvation Therapy Activated by the acidic tumor microenvironment, the Mg2Si NPs generate reactive silane, producing local hypoxia and SiO2 aggregates to block tumor blood capillaries and subsequently prevent reoxygenation. The deoxygenated tumor with no further oxygen supply will suffocate. Reproduced with permission from Macmillan Publishers Ltd: Nature Nanotechnology (Shi et al.4), copyright 2017. Chem 2017 2, DOI: ( /j.chempr ) Copyright © 2017 Elsevier Inc. Terms and Conditions
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