1. Microbial Diseases of the Respiratory System
Chapter 24, part B
Microbial Diseases of the Respiratory System

2. Tuberculosis
Mycobacterium tuberculosis: Acid-fast rod. Transmitted from human to human
M. bovis: <1% U.S. cases, not transmitted from human to human
M. avium-intracellulare complex infects people with late stage HIV infection
Figure 24.9

3. Tuberculosis
Figure

4. Tuberculosis
Figure

5. Tuberculosis
Figure

6. Tuberculosis
Treatment of Tuberculosis: Prolonged treatment with multiple antibiotics
Vaccines: BCG, live, avirulent M. bovis. Not widely used in U.S.

7. Tuberculosis Diagnosis: Tuberculin skin test screening
+ = current or previous infection
Followed by X-ray or CT, acid-fast staining of sputum, culturing bacteria
Figure 24.11

8. Tuberculosis
Figure 14.11c

9. Tuberculosis
Figure 24.12

10. Pneumomoccal Pneumonia
Streptococcus pneumoniae: Gram-positive encapsulated diplococci
Diagnosis by culturing bacteria
Penicillin is drug of choice
Figure 24.13

11. Pneumomoccal Pneumonia

12. Haemophilus influenzae Pneumonia
Gram-negative coccobacillus
Alcoholism, poor nutrition, cancer, or diabetes are predisposing factors
Second-generation cephalosporins