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Transcutaneous near-infrared spectroscopy for detection of regional spinal ischemia during intercostal artery ligation: Preliminary experimental results 

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Presentation on theme: "Transcutaneous near-infrared spectroscopy for detection of regional spinal ischemia during intercostal artery ligation: Preliminary experimental results "— Presentation transcript:

1 Transcutaneous near-infrared spectroscopy for detection of regional spinal ischemia during intercostal artery ligation: Preliminary experimental results  Scott A. LeMaire, MD, Lyssa N. Ochoa, MD, Lori D. Conklin, MD, Ron A. Widman, Fred J. Clubb, DVM, PhD, Akif Ündar, PhD, Zachary C. Schmittling, MD, Xing Li Wang, MD, PhD, Charles D. Fraser, MD, Joseph S. Coselli, MD  The Journal of Thoracic and Cardiovascular Surgery  Volume 132, Issue 5, Pages (November 2006) DOI: /j.jtcvs Copyright © 2006 The American Association for Thoracic Surgery Terms and Conditions

2 Figure 1 Graph showing percentage decline from baseline (mean ± SD) in Sro2 (rSO2) at T6-7 and T9-11 vertebral levels during sequential ligation of intercostal arteries. Once all vessels were ligated, decrease in Sro2 detected by lower sensor was significantly greater than that detected by upper sensor (P = .026). The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © 2006 The American Association for Thoracic Surgery Terms and Conditions

3 Figure 2 Representative graph showing increase in near-infrared light absorption at 810 nm after subarachnoid injection of indocyanine green dye (ICG). The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © 2006 The American Association for Thoracic Surgery Terms and Conditions

4 Figure 3 Representative histologic lateral corticospinal tract sections from upper (A, C, E) and lower (B, D, E) spinal cord. Compared with proximal sections, distal sections exhibited more pronounced ischemic changes, including increased vacuolization (arrowheads), retraction of neurons (arrows), and loss of nucleoli (double arrows). (Hematoxylin-eosin [A, B] and Luxol fast blue [C-F] staining; original magnifications ×20 [A-D] and ×40 [E, F]). The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © 2006 The American Association for Thoracic Surgery Terms and Conditions


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